How can sustainable feedstock materials reshape manufacturing while accelerating climate progress? The scale and urgency of the transformation required to fight climate change has never been more clear. Building hardware and software products, acquiring the funding and creating a diverse community to enhance talent capacity and to drive innovation, is essential to tackling this global environmental crisis. In this podcast, host Silicon Valley Bank (a division of First Citizens Bank) Climate Tech & Sustainability SVP Maggie Wong will be interviewing Mothership Materials CEO & Co-Founder Jo Marini to discuss producing feedstock materials for sustainable manufacturing, the importance of customer discovery and building stakeholder relationships and finding joy in product development. 

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Show Notes

  1. The biggest hidden bottleneck in sustainable manufacturing is not finished products—it’s the lack of scalable biological feedstocks to replace petroleum-based inputs.
  2. Modern industry still runs on an 1880s petroleum feedstock model, shaping everything from fabrics to coatings to adhesives.
  3. Replacing petroleum requires creating a biological equivalent of Standard Oil’s role—a scalable upstream materials platform.
  4. Mothership Materials focuses on producing foundational inputs (cellulose, sugars, lipids, antioxidants) rather than finished products.
  5. Many climate-tech and biofabrication companies already exist—but they cannot scale without reliable, affordable upstream feedstock supply.
  6. Agricultural waste is an underused resource that can become a primary industrial input instead of disposal cost or animal feed filler.
  7. The company’s modular micro-factories process waste directly at the source, avoiding centralized logistics bottlenecks.
  8. Locating production at waste sites enables a shift from global supply chains to regional circular manufacturing ecosystems.
  9. Their platform originated from medical blood-separation technology, demonstrating how cross-industry technology transfer unlocks new manufacturing models.
  10. The system operates as a continuous-flow closed-loop process, increasing efficiency while avoiding contamination and chemical inputs.
  11. Each deployment is configured like industrial “Legos”, customized to match the molecular composition of local waste streams.
  12. A single micro-factory can process up to 20 tons of raw material per hour, enabling rapid industrial throughput.
  13. Units cost roughly $150K–$250K and can reach payback in under a month, which dramatically improves adoption potential.
  14. The company’s first commercial targets include textile cellulose and fermentation-grade sugars, both high-demand industrial inputs.
  15. Biofabrication companies currently rely on food-grade sugar meant for humans, which is expensive and environmentally inefficient.
  16. Branding even upstream B2B inputs matters—the launch of “MicroMunch,” sugar designed specifically for microbes, doubled early demand within 48 hours.
  17. Trust-building is critical when introducing first-of-its-kind hardware; visual storytelling and partnerships help customers understand unfamiliar systems.
  18. Customer discovery shaped the company’s strategy early—its founder spent a full year speaking across industries before defining the first product path.
  19. The real opportunity is unlocking speed across the entire ecosystem: improving feedstock availability allows every downstream materials company to innovate faster.
  20. The long-term vision is a manufacturing future where clean materials are cheaper, more accessible, and no longer a tradeoff between cost, health, and sustainability.
About the speaker
Jo Marini Mothership Materials, CEO & Co-founder Member

Jo Marini is a 4x founder, MBA professor, United States Air Force Academy graduate, and IndieBio NY alum who specializes in systemic transformation within legacy industries. She is also a NYC EDC/NewLab Founder Fellow, Earthshot Innovation Prize Finalist and co-founder of Mothership Materials, using Targeted Molecular Recovery to sort ag & food wastes into feedstocks that power the foods, fuels, and fabrics of our future. Alongside her entrepreneurial ventures, Jo teaches Venture Studio in the MBA in Design Strategy program at California College of the Arts, the capstone course focused on turning world-changing ideas into resilient companies. Previously, Jo founded and led a venture fund and impact foundry aligning purpose-driven entrepreneurs with exponential impact models. Early in her career, she built and exited two award-winning regional supply chain ventures and was certified as a permaculture designer—unique experiences that shape her approach to regenerative systems and transformative business models.

About the host
Maggie Wong Silicon Valley Bank, Climate Tech & Sustainability SVP

Maggie Wong is an accomplished product management and capital markets leader with over 15 years of experience in driving product strategy, delivering global products, fundraising & capital allocation, and leading cross-functional teams. Outside of her role at Silicon Valley Bank to support New York / East Coast based climate tech companies and investors, she is also experienced in increasing program impact, growing community reach and implementing DEI initiatives at travel and fintech non-profits. Maggie is passionate about making a social impact for the next generation, tackling climate change and traveling. She is fluent in Mandarin and Cantonese and a beginner in Spanish.

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